Small molecule, re-formulation and re-purposing of generic risperidone, an anti-psychotic displaying anti-cancer activity when formulated in a specific lipid mixture
Primary indication: Pancreatic ductal adenocarcinoma
Follow-up indications: Any adenocarcinoma type
Licensed from: Tangent Reprofiling Limited, a member of the SEEK group
Published research: Clinical Pharmacokinetics of a Lipid-Based Formulation of Risperidone, VAL401: Analysis of a Single Dose in an Open-Label Trial of Late-Stage Cancer Patients. Suzanne J. Dilly, George S. Morris, Paul C. Taylor, Frederic Parmentier, Coralie Williams, Mohammad Afshar. Eur J Drug Metab Pharmacokinet 2019 (44) 557. https://doi.org/10.1007/s13318-018-00538-4
A chemical genomics approach to drug reproﬁling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment. Suzanne J. Dilly, Andrew J. Clark, Andrew Marsh, Daniel A. Mitchell, Colin W.G. Fishwick, Paul C. Taylor, Ricky Cain. Cancer Letters 393 2017 16-21.
Pimping up Drugs Recovered, Superannuated and Under Exploited Drugs - An Introduction to the Basics of Drug Reprofiling: Suzanne J. Dilly, George S. Morris. Curr Drug Discov Technol. 2017 Jun; 14(2): 121–126.